Phenylpropanoids and polyketides
Selleck Chemical LLC Palomid 529 (P529) S2238-1g
Palomid 529 (P529 SG 00529) inhibits both the mTORC1 and mTORC2 complexes reduces phosphorylation of pAktS473 pGSK3 S9 and pS6 Phase 1
![Medchemexpress LLC 6H-dibenzo[b,d]pyran-6-one, 8-(1-hydroxyethyl)-2-methoxy-3-[(4-methoxyphenyl)methoxy]- | 914913-88-5 | MFCD18633224 | 99.3% | C24H22O6 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000261568.png-250.jpg)
Medchemexpress LLC 6H-dibenzo[b,d]pyran-6-one, 8-(1-hydroxyethyl)-2-methoxy-3-[(4-methoxyphenyl)methoxy]- | 914913-88-5 | MFCD18633224 | 99.3% | C24H22O6 | 10MG
Palomid 529 is a small-molecule research inhibitor that targets both mTOR complex 1 (mTORC1) and mTOR complex 2 (mTORC2), modulating the PI3K/Akt/mTOR signaling pathway. It has been used in preclinical studies and early clinical research to reduce tumor growth, angiogenesis, and vascular permeability, and has been investigated for neovascular age-related macular degeneration.
- Dual inhibition of mTORC1 and mTORC2.
- Documented in peer-reviewed literature and public chemical databases.
- High reported purity suitable for analytical use.
- Suitable as an analytical standard and research reagent.
- Provided with batch-specific certificate of analysis data.
![Medchemexpress LLC 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-methoxyphenyl)- | 480-36-4 | 592.55 | 20 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Medchemexpress LLC 4H-1-Benzopyran-4-one, 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-methoxyphenyl)- | 480-36-4 | 592.55 | 20 MG
Linarin (Buddleoside) is an orally active and selective inhibitor of acetylcholinesterase (AChE). It exhibits various activities including anti-inflammatory, antioxidant, sleep aid and sedation, bone differentiation, anti-tumor, antibacterial, and antiviral properties. Linarin can be utilized in the study of diseases affecting the nervous system, osteoporosis, and cancer.
- Orally active and selective inhibitor of acetylcholinesterase (AChE).
- Anti-inflammatory properties.
- Antioxidant properties.
- Sleep aid and sedation.
- Promotes bone differentiation.
- Anti-tumor activity.
- Antibacterial properties.
- Antiviral properties.
- Useful for studying diseases such as those of the nervous system, osteoporosis, and cancer.
Medchemexpress LLC Palomid 529 | 914913-88-5 | 99.4% | C24H22O6 | 50 MG
Palomid 529 | 914913-88-5 | 99.4% | C24H22O6 | 50 MG
Apexbio Technology LLC Palomid 529 914913-88-5 10mg
Palomid 529 (CAS 914913-88-5) is a small-molecule inhibitor of the PI3K/Akt/mTOR signaling pathway targeting both TORC1 and TORC2 complexes It exhibits potent anti-proliferative activity in the NCI-60 cell line panel with GI50 values below 35 M In endothelial cell assays Palomid 529 inhibits VEGF- and bFGF-induced proliferation with IC50 values of 20 nM and 30 nM respectively The PI3K/Akt/mTOR pathway is implicated in tumor cell survival proliferation angiogenesis and resistance to apoptosis Palomid 529 has also demonstrated the ability to suppress radiation-induced expression of Id-1 VEGF MMP-2 and MMP-9 expanding its utility in studies of cancer biology and radiotherapy sensitization
Sigma Aldrich Fine Chemicals Biosciences Dihydrocoumarin 99% | 119-84-6 | MFCD00006881 | 100G
Dihydrocoumarin 99% | Purity: 99% | Mol Wt: 148.16 | 119-84-6 | MFCD00006881 | 100G
Sigma Aldrich Fine Chemicals Biosciences Dihydrocoumarin >=99%, FCC, FG | 119-84-6 | MFCD00006881 |
Dihydrocoumarin >=99%, FCC, FG | Purity: >=99% | Mol Wt: 148.16 | 119-84-6 | MFCD00006881 |
Sigma Aldrich Fine Chemicals Biosciences Dihydrocoumarin >=99%, FCC, FG | 119-84-6 | MFCD00006881 | 1KG
Dihydrocoumarin >=99%, FCC, FG | Purity: >=99% | Mol Wt: 148.16 | 119-84-6 | MFCD00006881 | 1KG
Aobchem Ethyl 2 2-difluoro-2-phenylacetate | ≥95% | CAS 2248-46-6 | C10H10F2O2 | 5g
Ethyl 2 2-difluoro-2-phenylacetate | ≥95% | CAS 2248-46-6 | C10H10F2O2 | 5g
Medchemexpress LLC Ethanone, 1,2-diphenyl- | 451-40-1 | MFCD00003081 | 25g
2-Phenylacetophenone has broad-spectrum efflux pump inhibition activity 2-Phenylacetophenone is a benzoin derivative used as a photoinitiator in vinyl polymerization[1]
Medchemexpress LLC Ethanone, 2-hydroxy-1,2-diphenyl- | 119-53-9 | 99.95% | 500 G
Benzoin (DL-Benzoin) is a PI3Kα inhibitor with anticancer effects. It inhibits the growth of colon cancer cell line (HCT-116) and has antiproliferative activities.
- PI3Kα inhibitor
- Anticancer effects
- Inhibits the growth of colon cancer cell line (HCT-116)
- Antiproliferative activities
![eMolecules 2091023-46-8 | 3-[(Trifluoromethyl)sulfonyl]phenacyl bromide | Apollo Scientific | MFCD31536707 | 331.100 | C9H6BrF3O3S | 95.000 | FC(F)(F)S(=O)(=O)c1cccc(c1)C(=O)CBr | 1g | 562429135](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502154799.JPG-250.jpg)
eMolecules 2091023-46-8 | 3-[(Trifluoromethyl)sulfonyl]phenacyl bromide | Apollo Scientific | MFCD31536707 | 331.100 | C9H6BrF3O3S | 95.000 | FC(F)(F)S(=O)(=O)c1cccc(c1)C(=O)CBr | 1g | 562429135
3-[(Trifluoromethyl)sulfonyl]phenacyl bromide | Apollo Scientific | 2091023-46-8 | MFCD31536707 | 331.100 | C9H6BrF3O3S | 95.000 | FC(F)(F)S(=O)(=O)c1cccc(c1)C(=O)CBr | 1g | 562429135
eMolecules 403793-28-2 | 1-Bromo-4-(butane-1-sulfonyl)benzene | Combi-Blocks | MFCD01124707 | 277.180 | C10H13BrO2S | 98.000 | CCCCS(=O)(=O)c1ccc(Br)cc1 | 1g | 117544112
1-Bromo-4-(butane-1-sulfonyl)benzene | Combi-Blocks | 403793-28-2 | MFCD01124707 | 277.180 | C10H13BrO2S | 98.000 | CCCCS(=O)(=O)c1ccc(Br)cc1 | 1g | 117544112